Advances in CFTR Therapeutics for Pediatric Patients with Cystic Fibrosis

In this module of the Eight-Part Cystic Fibrosis Series, Dr. Felix Ratjen will outline, with Dr. John P. Clancy, recent advances in CFTR therapeutics for the pediatric cystic fibrosis (CF) population. Dr. Ratjen will analyze clinical trial data, particularly safety and efficacy data, as it relates to clinical care for the younger patient. Both primary and secondary endpoints will be assessed and and discrepancies addressed. The faculty will highlight strategies for applying evolving clinical trial data to everyday practice to improve outcomes for pediatric CF patients.

TARGET AUDIENCE

These activities are designed for physicians, nurses, and other healthcare professionals involved in the management of patients with cystic fibrosis.

LEARNING OUTCOME STATEMENTS

At the conclusion of this activity:

KNOWLEDGE: Participants will self-report  knowledge gained based on current best practices for the management of pediatric patients with cystic fibrosis.

COMPETENCE/SKILL: Participants will self-report intent to change practice by applying evidence based best practices for the management of pediatric patients with cystic fibrosis.

EDUCATIONAL OBJECTIVES

Upon completion of this activity, participants will be better able to do the following:

  1. Analyze advances in CFTR therapeutics for pediatric patients with cystic fibrosis

FACULTY

John P. Clancy, MD (Chair)
Professor of Pediatrics
Director, Pulmonary Medicine Research
Co- Director, CF Research Development Program
Medical Director, Office of Clinical and Translational Research
Gunnar Esiason/Cincinnati Bell Chair in Life Sciences Research
Division of Pulmonary Medicine
Cincinnati Children’s Hospital Medical Center
Cincinnati, Ohio

Felix Ratjen, MD, PhD
Sellers Chair in Cystic Fibrosis
Head, Division of Respiratory Medicine
Senior Scientist, Translational Medicine
The Hospital for Sick Children
University of Toronto
Toronto, Canada

Disclosure of Conflicts of Interest

It is the policy of the Elsevier Office of Continuing Medical Education and the Elsevier ANCC accredited provider unit that all faculty, instructors, and planners disclose real or apparent conflicts of interest relating to the topics of this educational activity. 

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

FacultyRelationship Identified With:
John P. Clancy, MD

Consultant/Advisor: Gilead

Grant/Research Support: Bayer AG, Concert Pharmaceuticals, Inc., Vertex Pharmaceuticals Incorporated, ProQR Therapeutics

Speaker's Bureau: Genentech, Inc.

Felix Ratjen, MD, PhD

Consultant/Advisor: Vertex Pharmaceuticals Incorporated

Grant/Research Support: Vertex Pharmaceuticals Incorporated

Non-faculty: Sandy Breslow; Alison Kemp; Marilu Kelly, MSN, RN, CNE; Bernard M. Abrams, MD; Timothy Hayes, MD, PhD; Emma Boring; Nicole Brestowski and Chelsey Benedek hereby state that neither they nor their spouse/life partner have any financial relationships to products or devices with any commercials interest related to the content of this activity of any amount during the past 12 months.

Financial Support

This activity has been supported by an independent educational grant from Vertex Pharmaceuticals Incorporated.

PROVIDER INFORMATION

Provided in collaboration with the Elsevier Office of Continuing Medical Education, Elsevier and AcademicCME.

CME CREDIT (PHYSICIANS)

The Elsevier Office of Continuing Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing education for physicians.

The Elsevier Office of Continuing Medical Education designates this enduring material for a maximum of 0.5 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CNE CREDIT (NURSES)

This continuing nursing education activity, provided by Elsevier, awards 0.45 contact hours for nurses. Elsevier is accredited with distinction as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Elsevier is provider approved by the Florida Board of Nursing, Provider #50-4681, and the California Board of Registered Nursing, Provider #CEP 3257.

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of EOCME, Elsevier, and AcademicCME. EOCME is accredited by the ACCME to provide continuing medical education for physicians.

CME/CNE INQUIRIES/SPECIAL NEEDS

For all CME inquiries or special needs, please contact elsevierCME@elsevier.com.

For all CNE inquiries or special needs, please contact p.harvey@elsevier.com.


Disclosure of Unlabeled Use: This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The Elsevier Office of Continuing Medical Education, Elsevier, AcademicCME and Vertex Pharmaceuticals Incorporated do not recommend the use of any agent outside of the labeled indications.

Disclaimer: Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Course summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit(s)™
  • 0.45 Nursing Contact Hours
  • 0.50 Non-physician
Course opens: 
09/15/2017
Course expires: 
09/14/2018
Rating: 
0

Available Credit

  • 0.50 AMA PRA Category 1 Credit(s)™
  • 0.45 Nursing Contact Hours
  • 0.50 Non-physician

Accreditation Period

Course opens: 
09/15/2017
Course expires: 
09/14/2018
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